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Overview         (For age - group : Above 16 )

World's first movies on bird flu - This is the first part of bird flu the virus - This animated, 45 minute, movie arms you with detailed information on virus, it answers those questions that had been bothering you but did not know whom to ask?, like how can a "bird virus" infect human beings, How can the virus jump from chicken to humans? If this H5N1 virus has been present since 1997, why is there no medicine or vaccine available even today to fight it?

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Time (hr:min:sec) 0:45:0
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Bird Flu - The virus movie Part 1:
Content : Disease
Type : Animation (advanced)
Duration : 45 minutes

The animation shows in details the following

    Topics Covered in Part 1 :
  • Seeing the real virus
  • Viral structure, RNA, DNA
  • Virus - a life form?
  • How virus binds to a cell?
  • Avian & human virus-basic
  • Strains - shift, drift and recombination in detail
  • Immune system - antibody action (basic concept)
  • Specific nature of viral attachment
  • Previous instances of virus jumping on to humans
  • Influenza virus
  • Influenza A, B, C difference
  • Mechanism of infection of influenza virus
  • Hemagglutinin & Neruraminidase action
  • Classifying influenza A viruses
  • Common Influenza viruses-human
  • Common influenza viruses-birds
  • Mutation example-H5N2

    Available in Part 2 --
  • How virus binds to a cell?
  • Avian & human virus-detailed
  • Strains - shift, drift and recombination in detail
  • How bird virus infects humans
  • Why spreading in Asia?
  • Why pigs are mixing vessels
  • Explanation based on sialic acids receptors and ciliated epithelium
  • Bird flu transmission
    • -Direct from birds
    • -through pigs (based on sialic receptors)
    • -human to human transmission

Snapshots         
Mia shows the virus to Sid and Becky through electron microscope
Dr. Jenny explains the difference between a bird flu virus and a human flu virus
Influenza virus are of three types A, B,C
Mia shows the real virus to Sid and Becky through electron microscope
Dr. Jenny elucidates the difference between a bird flu virus and a human flu virus
Influenza viruses are of three types A, B,C
Jenny explains about H5N1 virus
Dr. Jones explain about the RNA/DNA part of the virus
Mia explains about the infection process of a bird
Jenny explains about H5N1 virus
Dr. Jones explain about the RNA/DNA part of the virus
Mia tells Sid about the infection process of a bird
Human and bird flu viruses combine Mutation of virus takes place in a cell using reassortment creating its copies or virion
Dr. Jones explains the difference between influenza and other viruses
Human and bird flu viruses combine to create a new deadlier virus
Mutation of virus takes place in a cell using reassortment creating its copies or virion
Dr. Jones clarifies the difference between influenza and other viruses
Becky learns why vaccines dont work
Virus has previous jumped to human beings from animals before also There are combinations for which antibodies are present
Becky learns why vaccines don't work
Virus has previous jumped to human beings from animals before also
There are combinations for which antibodies are present
Details of the animation/ movie /software

There are two parts of this movie both are sold separately, this is the part 1, the part 2 deals with viral transmission to humans.

Virus is a strange entity it is "un-dead" and when it comes in contact with a living cell it becomes alive and causes diseases and deaths. This movie takes you onto a journey of discovering the virus. The movie explains it in an easy to understand, interactive format. It answers many questions, some of them are given below. There are two more movies on bird flu, go to their pages on our site to get more details about this virus

Some of the Questions Answered on Virus

1.What are influenza viruses? What do they look like ?
2.How are "bird flu" viruses different from "human flu viruses"?
3.How are strains produced due to mixing of bird and human viruses?
4.How does mixing of bird flu virus and human flu virus take place?
5.Is the present instance of virus jumping from bird to human a lone one?
6.Can a virus affect any type of cell whether human, plant or an animal cell?
7.How big is a virus?
8.How is an entirely new virus strain created?
9.What is this antigenic shift and drift?
10.What are those spring like things inside the virus?
11.How do virus mutate?
12.What is meant by antigenic shift, drift and recombination?
13. Can you show us the attachment of bird flu virus to human ciliated cells?
14.What is transmission mechanism of virus from human to human?
15.How do they cause us harm, if the body can neutralize them?
16. How can the virus "jump" from chicken to humans?
17.If this H5N1 virus has been present since 1997, why is there no medicine or vaccine available even today to fight it?
18.What is virus, what does it look like, how does it function? Are they alive?
19.Can our body not recognize them as invaders and prevent them from causing harm?
20.What is this influenza virus type A? What is this H and N in H5N1?

Six powerful animations explaining everything about bird flu
Surviving bird flu Protecting poultruy and pet birds from bird flu
bird flu - the virus part 1 Bird flu the virus 2
bird flu seminar Bird flu map

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Q & A
Q1: can u give me some information about flash animation on bird flue kisna 5/3/2009
Ans:
   
Q2: can you give me web site so that i can see full video of virus sonia 30/4/2008
Ans:
   
Q3: what is the structure of the gene arrangement of H5N1 virus Okudo Chioma Catherine 11/3/2008
Ans: The H5N1 genome has eight segments (1–8), each segment codes for a protein: polymerase (PB2), polymerase (PB1), polymerase (PA), hemagglutanin (HA), nucleocapsid (NC), neuraminidase (NA), matrix protein 2(M1, M2) and nonstructural protein (NS) respectively. These eight genes make up the flu’s genome, or complete collection of genes
   
Q4: what are the clinical signs and symptoms in birds and is there any diagram to show us that? Dr.omar 20/2/2007
Ans: In LPAI, in poultry, mostly clinical signs are absent, indications are mild respiratory disease, depression, and decrease in egg production; Clinical signs for HPAI are: depression, excessive thirst, open mouth breathing, loss of appetite, decreased egg production, nervousness, swelling or blue discoloration of combs and wattles, edema around eyes, coughing, star gazing, sneezing, rales and excessive lacrimation. Sudden death can occur. We are putting up a flash based diagram in article section.
   
Q5: how virul living or non living organism? sumit 19/2/2007
Ans: Viruses are codes that are floating in a medium whether air, water and blood or involuntarily sticking to surfaces something like dust particles. However once they come in contact with a receptive living cell they become active, you can imagine them to be like an autorun CD that is inert or non-active when outside a computer (analogous to a cell) but automatically runs its program (or becomes “alive”) when inserted in a CD drive (a cell receptor in case of a virus) and takes over the computer.
   
Q6: Please show me about H5N1 antigenic shift and antigenic drift animation. Numhom 26/1/2007
Ans: Antigenic drift: It is a continuous but permanent mutation in the genetic material of the virus; it modifies the shape of the receptors of the virus so that antibodies effective against it before fail to attach to it, making the previous vaccine useless. Here (virus remains the same. In case of antigenic shift, an entirely new virus is formed due to combination of virus of two different species. Here large fragments of genes are replaced by different ones. Influenza virus readily undergoes this.
   
Q7: i am very thankful to you and like your efferts to spread the knowldge.again i appriciate you. ammara 21/11/2006
Ans: Thanks ammara, it is the generous appreciation of visitors like you that spurs us on to do more, please do keep on asking questions and giving us feedback.
   
Q8: what did ment by influenza.from wich language is this word. ammara 17/11/2006
Ans: Influenza (flu), is an infection of birds and mammals caused by an RNA virus. It originated in 15th century Italy from “influential” meaning in ('in', of course) and fluere ('to flow'). It referred to the power the movements of the cosmos held over inhabitants of earth. Used in 1439 by Italian doctors for influenza di febbre scarlattina, or 'scarlet fever'. It first came into English in 1743 when it was borrowed from an outbreak in Europe to connote a disease resulting from miasma (bad air).
   
Q9: explain the life cycle of the virus H5N1. Noovera 21/7/2006
Ans: The life cycle consists of stages like attachment, penetration, uncoating, biosynthesis, assembly and release of virions, since this space is insufficient we are including a more detailed answer in our forums.
   
Q10: hemagglutinin detailed structure mohammed mahmood 4/4/2006
Ans: The detailed structure and description of hemagglutinin is not there in this animation, we are right now developing a separate product for hemagglutinin and neuraminidase containing detailed mechanism, meant for medical and microbiology reference but it will take some time. The present product is directed towards those with high curiosity but not having advanced knowledge to quench it.
   
Q11: i want diagrammatic representation of life cycle of H5N1 suresh kumar.H 6/2/2006
Ans: This has been a regular request by a lot of people, the good news is that we are in the final stages of designing such a diagram, the only debate is should it be in printed poster format or in flash format, thanks for the request in next 15 days we will release such a diagram, please keep on checking this page
   
Q12: How do avian influenza virus mutate? suresh kumar 3/2/2006
Ans: by mainly three processes 1) antigenic shift - two different AI virus infect a cell, nucleic acid mix, new virus emerges 2) antigenic drift - virus affects a cell in the reformation of virion - error takes place, new virus slightly different from old 3) recombination - same virus say H5N1 , infects a cell, re-assortment of genes takes place, H5N1 that emerges is slightly different one, actually this is the method H5N1 has been using to evolve
   
Q13: what is main overview of bird flu? suresh kumar 3/2/2006
Ans: We will focus only on "H5N1”, bird flu with reference to birds has been extremely virulent causing nearly 100% fatality in domestic birds, mainly spreads through water birds to domestic, has been infecting Asia and some parts of Europe, in context with humans the mortality has been 50-60% with no proven human - human transmission, largely limited to Asia, spreads due to close contact with infected birds. Is not airborne and there is no vaccine, with antiviral medicine “Tamiflu” still not efficac
   
Q14: what kind of treatment is provided for protection of avian influenza virus? suresh kumar 3/2/2006
Ans: Please refer to the article section
   
Q15: How are "bird flu" viruses different from "human flu viruses"? suresh kumar 3/2/2006
Ans: Gene structure, glyco proteins and the way the receptors bind to epithelial cells, human AI virus binds to non-ciliated ones while bird virus primarily binds to ciliated ones
   


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